ADVANCES IN HIGH THROUGHPUT PROTEOMICS PROFILING IN ESTABLISHING POTENTIAL BIOMARKERS FOR GASTROINTESTINAL CANCER

Advances in High Throughput Proteomics Profiling in Establishing Potential Biomarkers for Gastrointestinal Cancer

Gastrointestinal cancers (GICs) remain the most diagnosed cancers and accounted for the highest cancer-related death globally.The prognosis and magic bean tiger treatment outcomes of many GICs are poor because most of the cases are diagnosed in advanced metastatic stages.This is primarily attributed to the deficiency of effective and reliable early

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Associations between maternal plasma zinc concentrations in late pregnancy and LINE-1 and Alu methylation loci in the young adult offspring.

BackgroundIn animal models, prenatal zinc deficiency induced epigenetic changes in the fetus, but data in humans are lacking.We aimed to examine associations between maternal zinc levels during pregnancy and DNA methylation in LINE-1 and Alu repetitive sequences in young adult offspring, as well as anthropometry and cardiometabolic parameters.Metho

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Pakistani Urdu Short Story and Search for National Identity

This study delves into the rich assortments of Pakistani Urdu short stories to disentangle the aspects that weave the narrative of national identity.By cultural diversity, historical complexities, and socio-political challenges, Urdu literature serves as a powerful medium for authors to articulate and question the concept of national identity.Throu

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Disruption of CTCF-YY1-dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription.

The complex life cycle wiha 77891 of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted.Upon epithelial differentiation, E6/E7 transcription is increased through unknown mechanisms to drive cellular proliferation required to support virus replic

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